Question
Dietary study. Clinical investigators recruited health adults with moderately high cholesterol for a clinical trial to compare three diets: A, B, and Control. The 30
Dietary study. Clinical investigators recruited health adults with moderately high cholesterol for a clinical trial to compare three diets: A, B, and Control. The 30 participants were randomly assigned to one of the three diets by age group (<50 or 50+) and the intervention lasted 6 weeks. The primary endpoint was change in cholesterol from baseline to study end. The data from the study are provided below:
ID treatment age group Change in cholesterol
101 A <50 -44
102 A <50 -50
103 A <50 -77
104 A <50 -64
105 A <50 -48
106 A 50+ -71
107 A 50+ -27
108 A 50+ -31
109 A 50+ -44
110 A 50+ -56
111 A <50 -43
112 A <50 -52
113 A <50 -70
114 A <50 -46
115 A <50 -42
116 A 50+ -79
117 A 50+ -82
118 A 50+ -87
119 A 50+ -35
120 A 50+ -77
121 control <50 -20
122 control <50 -7
123 control <50 1
124 control <50 -27
125 control <50 3
126 control 50+-3
127 control 50+ 24
128 control 50+ 4
129 control 50+ -25
130 control 50+ 13
a.What type of experimental design is this? Why?
b.What are the possible tests of hypothesis that you can make?
c.Provide a table of descriptive statistics for the trial.
d.Perform the analysis and provide your ANOVA table.
e.What are your conclusions? How do you justify them?
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