Digestion and absorption of hydrophobic nutrients (such as fats and lipid soluble vitamins) depends on cholesterol derivatives known collectively as bile acids. Bile acid formation is negatively regulated by the binding of bile acids to the Farnesoid X Receptor (FXR). A scientist is studying mutated versions of FXR to better understand its mechanism of action. (A) One mutant FXR protein binds (a single molecule) of cholic acid with a K: = 100.0 nM. Draw a plot of (percent FXR bound to cholic acid) vs. cholic acid concentration (L). Please indicate Ky on the graph you draw, as well as appropriately label the axes. 1 (B) Another FXR mutant oligomerizes and cooperatively binds cholic acid molecules. On your above plot, sketch the binding curve for that mutant Digestion and absorption of hydrophobic nutrients (such as fats and lipid soluble vitamins) depends on cholesterol derivatives known collectively as bile acids. Bile acid formation is negatively regulated by the binding of bile acids to the Farnesoid X Receptor (FXR). A scientist is studying mutated versions of FXR to better understand its mechanism of action. (A) One mutant FXR protein binds (a single molecule) of cholic acid with a K: = 100.0 nM. Draw a plot of (percent FXR bound to cholic acid) vs. cholic acid concentration (L). Please indicate Ky on the graph you draw, as well as appropriately label the axes. 1 (B) Another FXR mutant oligomerizes and cooperatively binds cholic acid molecules. On your above plot, sketch the binding curve for that mutant