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Draw compound 13 in your answer book and circle all the protecting groups What reagent(s) would you choose to selectively remove just the silyl ethers
- Draw compound 13 in your answer book and circle all the protecting groups
- What reagent(s) would you choose to selectively remove just the silyl ethers from 13?
- Using your answers to parts (v) and (vi) above, explain what is meant by an orthogonal protecting group strategy.
TBSO OBn OTPS OBn OTBS TPSO- a. n-BuLi, THE NNHSO2AR H 8 10 TBSO TBSO TBSO OTPS PS OTPS c. LIAIH4, Et,0 OBn OBn OBn d. H. to to 11 13 12 TPS = tert-butyldiphenylsilyl (-Si((C6H5)2C(CH3)3)) TBS = tert-butyldimethylsilyl (-Si((CH3)2C(CH3)3)) Bn = benzyl (CH2PH) acac = acetylacetonato (CH3COCH2COCH3) BuLi = butyl lithium (CH3CH2CH2CH2LI) b. II .....
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Business Forecasting With Forecast X
Authors: Holton Wilson, Barry Keating, John Solutions Inc
6th Edition
73373648, 978-9339220426, 9339220420, 978-0073373645
