E = equivalent exposure for the work shift

C = concentration during any period of time in which the concentration remains constant

T = duration of time in hours of the exposure

The regulation further stipulates that no employee can be further exposed to the gas when the value of E exceeds the 8-hour time-weighted average limit set for the given substance. Using the formula above, determine if the employer complied with this regulation if a worker is exposed to CO concentrations throughout the workday as follows: 45 ppm for 3.25 hours; 75 ppm for 2.5 hours; 50 ppm for 1.5 hours and 60 ppm for 45 minutes. Explain CO poisoning and the interaction of CO with hemoglobin.