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EBV Infection Smoking (exposure) Incidence per 100,000 (no decimal) Attributable Risk per 100,000 (no decimal) Relative Risk per 100,000 (two decimals) Negative No 5 0

EBV Infection Smoking (exposure) Incidence per 100,000 (no decimal) Attributable Risk per 100,000 (no decimal) Relative Risk per 100,000 (two decimals) Negative No 5 0 1.00 Yes 8 3 1.60 Positive No 10 5 2.00 Yes 15 10 3.00 Using the table above, calculate the synergy index (SI) by VanderWeele TJ et al and select the appropriate conclusion. Assume no random error or bias. A) SI = 0.10, there is some evidence of antagonistic interaction. B) SI = 10.00, there is some evidence of synergistic interaction. C) SI = 0.80, there is evidence of antagonistic interaction. D) SI = 1.25, there is some evidence of synergistic interaction

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