Question
Explain using mechanistic arguments involving Newman projections or other three-dimensional formulas why the reaction of 2-bromo-1,2-diphenylpropane (either enantiomer) with sodium ethoxide (EtONa) in ethanol (EtOH)
Explain using mechanistic arguments involving Newman projections or other three-dimensional formulas why the reaction of 2-bromo-1,2-diphenylpropane (either enantiomer) with sodium ethoxide (EtONa) in ethanol (EtOH) at 80°C produces mainly (E)-1,2-diphenylpropene [little of the (Z) diastereomer is formed].
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Organic Chemistry
Authors: Francis A. Carey
4th edition
0072905018, 978-0072905014
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