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In wild type E. coli a 3'- G-T-A- 5' triplet of DNA nucleotides is transcribed into a codon that is translated into an amino

   

In wild type E. coli a 3'- G-T-A- 5' triplet of DNA nucleotides is transcribed into a codon that is translated into an amino acid in a functioning polypeptide. If there is a nucleotide pair substitution mutation that swaps the adenine in the DNA triplet for a cytosine, this would result in: O there being no change in the primary, secondary or tertiary structure of the mutant polypeptide. O there being a change in primary structure and possible changes in the secondary and tertiary structure of the mutant polypeptide. O a premature stop codon being generated so the mutant polypeptide would be shorter than the wild type. O a codon frameshift causing extensive missense that means all the amino acids in the polypeptide after the mutation would be different from the wild type. Figure 5. The codon table for MRNA Second Base A UUU UCU UAU UGU Phe Tyr Cys UUC UCC UAC UGC Ser UUA Stop UCA UAA UGA Stop A Leu UUG UCG UAG Stop UGG Trp CUU CCU CAU CGU His CC CCC CC CGC Leu Pro Arg CUA CCA CAA CGA Gin CUG CCG CAG CGG AUU ACU AAU AGU Asn Ser AUC Ile ACC AAC AGC Thr AUA ACA AAA AGA Lys Arg Met or Start AUG ACG AAG AGG G. GUU GCU GAU GGU Asp GUC GAC - GCC GGC G Val Ala Gly GUA GCA GAA GGA GAG - Glu GUG GCG GGG First Base Third Base Use Figure 5 to answer the following question.

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