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Find the interactions involved in: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with belinostat belinostat (a) Identify all the
Find the interactions involved in: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with belinostat belinostat (a) Identify all the interactions of belinostat with the Zn2+ ion (the type of interaction and the atoms/groups of belinostat involved) Example: metal coordination between Zn2+ and oxygen atom of hydroxamic acid OH of belinostat (b) Identify all other interactions of Zn2+ ion (the amino acid involved, the atom/group of the amino acid, type of interaction) (c) Identify the type of interaction and the amino acid involved in all the interactions shown by arrows in the figure below. (Example - ionic interaction with PHE 235). If it is hydrogen bonding with a water molecule, "write hydrogen bond with water molecule
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