H425 Instructions for Cohort reading response Instead of the usual generic reading response prompts, please address each of the following questions as you write your response to the Wennberg article. Note that you are asked to address all of the questions that appear below, rather than choosing one as is customary for the generic reading responses. Please bring a copy of the article to class on the day this assignment is due, and be prepared to discuss these and other issues during class. 1. Describe the cohort: how was the cohort recruited, how long were they followed, how many participants were lost to follow up? 2. How and when was information on the exposure (focus on TV viewing) and outcome (metabolic syndrome) ascertained? 3. From Table 1, do daily smokers (at age 16) on average watch more or less TV than non-smokers? 4. How does Table 2 suggest a dose-response association between TV viewing and metabolic syndrome? 5. How do the investigators attempt to deal with the inherent difficulty of cohort studies to determine causal relationships? Are you convinced? 6. Do the authors address the limitations and generalizability of their sample to other populations? How generalizable do you think these results are? 7. How would you design an RCT to address the same research question as this paper