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Hemoglobin carries oxygen and carbon dioxide throughout the body. The oxygen saturation curve for hemoglobin ( Fraction or percentage of hemoglobin that is saturated )

Hemoglobin carries oxygen and carbon dioxide throughout the body. The oxygen saturation curve for hemoglobin (Fraction or percentage of hemoglobin that is saturated) can be approximated using
the Hill Equation: This equation can be re-arranged as follows (see attached)
You can plot ln(Y/(1-Y)) vs ln(PO2) to estimate n. Use this data to
estimate the value of P50 as well.
a. Use basic linear regression (or calculate the value of n using the linear portion of the transformed data (using y= mx+b) using the linear portion of the transformed data (Hint: You can visually select
the points from your transformed data). What is your value for n? Make sure you plot the measured values and your predicted values on the same graph.
b. What happens to your curve if P50=20,28 and 35 mmHg?(Plot all three on one curve). How the Hill Equation:
Y=(pO2)n(P50)n+(pO2)n
This equation can be re-arranged as follow:
ln(Y1-Y)=n**ln(pO2)-n**ln(P50)do
these changes affect the predicted oxygen transport?
c. What happens to your curve if n =2,2.5, or 3?(Plot all three on one curve). How do these changes
affect the predicted oxygen transport?
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