how best can you answer these questions

1.after travelling through the late endosome,what is the fate for materials ingested by endocytosis?explain

2.explain the feature of the Transformation from an early to a late endosome in the pH

3.position the Late endosome in the nucleus

4. Following internalization, vesicle^-bound materials are transported to?

5.justify accordingly why; Receptor down regulation leads to a decrease in the sensitivity of the cell towards further stimulation.

6.what is the interestingcomponent do you knowabout Dynamin?

7.interelate the roles of the AP2 and the clathrin^-mediated endocytosis

8.A molecule of clathrin has a ______________ structure;demonstrate

9.how do the roles of the clathrin and Receptor^-mediated endocytosis (RME)overlap?

10.propse and explain the nature of the operations of thereceptor^-mediated endocytosis in regard to the cell uptakes extracellular material