How does glucokinase in the liver differ from hexokinase in muscle?

A. glucokinase produces glucose as the last step in gluconeogenesis

B. glucokinase use GTP-Mg2+ rather than ATP-Mg2+ for phosphorylation

C. glucokinase does not change conformation upon binding of glucose

D. glucokinase substrate specificity is limited to glucose phosphorylation

E. glucokinase phosphorylates the C1 position of glucose to produce G1P