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I' An HGT was designed to test the effectiveness of naltrexone, an opiate receptor antagonist, as a treatment for alcohol dependence. Subjects with chronic severe

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I' An HGT was designed to test the effectiveness of naltrexone, an opiate receptor antagonist, as a treatment for alcohol dependence. Subjects with chronic severe alcohol dependence were randomly assigned to either 3 months of naltrexone treatment or 3 months of placebo treatment. The number of drinks per drinking day was compared between the two groups. Let pl: population mean number of drinks per drinking day for those on Naltrexone and pl: population mean number of drinks per drinking day for those on placebo. The data from the study are summarized in the table below. Naltrexone in: = 195i Placebo l": = 195) Mean Number of drinks -er drinldn d - mam-.351- Standard Deviation of Number of drinks per drinking day m lnvestigators want to test if there is a difference between the two groups using a 5% significance level. The value of the test statistic for the appropriate test is -1.58 and the corresponding p-value is 0.12. Based on this information, the 95% confidence interval for the true difference in mean number of drinks per drinking day between those taking Naltrexone and those taking placebo would: 0 not include 0 and not include the estimated difference in the means not include 0 but include the estimated difference in the means include 0 but not include the estimated difference in the means include 0 and inclur Screenshot lifference in the means 3000 include 0 and not include 0

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