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i) Apply Lipinskis Rules to the structure of indinavir. (4 marks) ii) What does your Lipinski analysis tell you about the suitability of indinavir as

i) Apply Lipinski’s Rules to the structure of indinavir. (4 marks)

ii) What does your Lipinski analysis tell you about the suitability of indinavir as a drug? Briefly explain the limitations of this analysis. (2 marks)

N. OH OH Indinavir 1 Molecular Weight: 613.80 logP: 2.49 IZ ZI

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