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.-'i close-up image of a group of three cells ret'eals the following contact angles between them. The darlcljc shaded cell {Cell C} is a particular
.-'i close-up image of a group of three cells ret'eals the following contact angles between them. The darlcljc shaded cell {Cell C} is a particular lcind of cancer cell. The boundaries between the cells are assumed to carry tension, and the cell edges indicate the direction along which those tensions act. Treat the triple junction _T as a point that is subjected to different tensions acting along each of the three cell-cell interfaces. Iote that the lengths of the sides and of the arrosw shown along them are unrelated to the magnitudes of the forces theyr carry. {D r. Brodland'sl ab does cancer research using exactly these kinds of ideas}. .Jissunte that the tension T .sa along the edge be'we en cells .l and E is 50p}; 1What tensions must act along the AC and EC boundaries for the triple junction between the three cells to be in equilibrium. In adddressing this question. you may find it useful to choose a coordinate STE'EEIII that is aligned with one or more of the cell edges. What does your analysis tell you about the relative strengths of the tensions along boundaries between normal cells {like the AB boundary} and boundaries with cancer cells (the AC and BC boundaries}? 'iTllat does it tell you about the tensions along different boundaries of similar type {i.e.. the tensions along the AC." and EC boundaries?)
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