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ICE NEVIEW View Help contain viruses. Unless you need to edit it's safer to stay in Protected View Question 6 Erable Editing Benzoylglycine, the principal

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ICE NEVIEW View Help contain viruses. Unless you need to edit it's safer to stay in Protected View Question 6 Erable Editing Benzoylglycine, the principal metabolite of benzoic acid, can be prepared synthetically from bromobenzene. Write mechanisms for each step in its synthesis. (10 marks) OH oor Bromobenzene Benzoylglycine Question 7 Write a brief summary of the major Phase Il metabolic conjugation reactions which typically occur with drug substances. Use the example ketoprofen (below) to illustrate your answer. Why are conjugation reactions important in the detoxification of drugs? CH, CO, Ketoprofen (10 marks) 8

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