If a cell's genome is completely known, is it possible to determine the cell's transcriptome-the sequence of all the RNAs being produced by the cell-without additional information? Why or why not? No, because transcription is a completely random and irreproducible process. Yes, because the transcript of any gene is predictable from its DNA sequence. Yes, because the transcriptome is simply the genome with U in place of T. No, because different promoters and RNA processing events are active based on different cellular conditions