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If you want to develop a new molecular structure based on the molecular structures of direct-acting alpha2 agonist drugs, which molecule would be the most

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If you want to develop a new molecular structure based on the molecular structures of direct-acting alpha2 agonist drugs, which molecule would be the most suitable for you please explain HO NH HN HN HN 3000 euro HN HO 1 2 3 4 5

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