In 1950, Richard Doll and A. Bradford Hill published findings from a case-control study that examined a hypothesized relationship between lung cancer and smoking. They collected data from 709 lung cancer patients and 709 patients with diseases other than cancer. The patient groups were matched on age and sex. All participants received the same interview about their smoking history. Doll and Hill found that 688 of the lung cancer patients and 650 of the patients with other diseases had a history of smoking.

How can we put this in 2x2 or 2x3 table?

1. what is the outcome, exposure, cases and control of this study
2. What are the odds of smoking among patients with lung cancer?
3. What are the odds of smoking among patients with other diseases?
4. How to calculate the odds ratio (of exposure to smoking among those with lung cancer compared to those with other diseases
5. What would be the interpretation of your finding from the above question?
6. what is the strength and limitation of this study?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2038856/pdf/brmedj03566-0003.pdf