In order to test whether a new drug affects mental alertness, a sample of 5 patients is administered a test before and after they receive the drug. The researcher claims that there is a change in alertness. At the 1% level of significance, is there a change in alertness. The mental alertness test gave the following results:

Stress Level Life-Span Low Moderate High Total Short 26 35 42 103 Average 37 49 35 121 Long 51 26 15 92 Total 114 110 92 316March Rainfall in 3 7 2 S inches x Crop yield in S 12 4 12 6 bushels per acre y4000 B.C. 1850 B.C. 150 A. D. 131 129 128 138 134 138 125 136 136 129 137 139 132 137 141 135 129 142 132 136 137 134 138 145 138 134 137Before 10 7 5 9 11 After S 4 6 7