In the following enzymatic reaction scheme (1) where E, S, ES, EAc, and P represent an enzyme, a substrate, a noncovalent enzyme-substrate complex, a covalent enzyme-substrate complex, and a product, respectively, ka k3 ki S+E ZES EAc E + P (1) k-1 A ratio of ky ka determines how much fraction of enzyme molecules is present in the form of the covalent enzyme-substrate complex (=EAC) for a given [S]. In which range of the kz/kz value, can all enzyme molecules be assumed to be present in the form of EAC (ie, [EAc] {[E]+[EAc]+[ES]} 1) for any value of [S]? Show your work for credits. Apply PSSA on ES and EAC