Question
Investigators conducted a study to evaluate the use of a screening test of specific hormones in the blood to assess whether or not the fetus
Investigators conducted a study to evaluate the use of a screening test of specific hormones in the blood to assess whether or not the fetus of a pregnant women is likely to have Down syndrome.10000 pregnant women underwent the screening test and scored either positive or negative depending on the levels of hormones in the blood. There were 1255 women with positive test; from them, 285 women had an affected fetus. There were 9700 unaffected fetus; 8730 of these had negative test results.
What was the sensitivity, specificity, positive predictive value and negative predictive value of the test?Interpret the results (Show your work including developing a 2 X 2 table).
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