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IV. Problem solving (please show your steps) 1. The following table gives # of genotype at two blood group loci in humans. (16 points) MM
IV. Problem solving (please show your steps) 1. The following table gives # of genotype at two blood group loci in humans. (16 points) MM Mm mm SS 910 320 50 Ss 1470 780 170 SS 850 750 70 A. estimate the allele frequencies of each locus (8 points) B. Estimated linkage disequilibrium (D) (Equations gi=PMPs +D, gi=(2N11 +N12+N21)/2(N-N22). (4 points) C. . Estimate Standardized disequilibrium (D'). (Keep in mind: D=D/Dmax, Dmax = min (PMPs, Pinalis) if D > 0, Dimax=min(PMPs, Linalis) if D 0, Dimax=min(PMPs, Linalis) if D
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