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k1 1. Derivation of a rate expression for two consecutive reactions (10 points): Consider the following reaction sequence: k3 ks S+E= [ES]1 [ES]2 +P+E k2

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k1 1. Derivation of a rate expression for two consecutive reactions (10 points): Consider the following reaction sequence: k3 ks S+E= [ES]1 [ES]2 +P+E k2 k4 Develop a suitable rate expression for the product P formation (r = ks [ES]2] by using: a. the quasi-equilibrium (Michaelis-Menten) approach b. the pseudo-steady-state (Briggs-Haldane) approach Show all of your algebraic steps for both methods. =

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