Question
Make into viable MATLAB code that produces the same answer? Question: Kidneys are the body's natural defense mechanism against acidosis. The proximal tubules produce NH3
Make into viable MATLAB code that produces the same answer?
Question:
Kidneys are the body's natural defense mechanism against acidosis. The proximal
tubules produce NH3 to counter the effects of hydrogen ions by removing them from the blood stream to form NH4+. Assuming that the blood pH is at 7.2, how many of moles of NH3 must be produced to raise the blood pH back to a normal 7.4? The Ka of NH4+ is 5.6 x 10^-10 M. You can assume that there is no NH3 initially in the blood. The initial concentration of NH4+ in the blood is 60 ug/100 mL. Assume that the bicarbonate buffering system is at normal levels for a blood pH of 7.2.
Work:
NH3 + H20 ------> NH4+ + OH-
its the reactions taking place there
given the Ka of NH4 + is 5.6 x 10^-10 M.
so Kb of ammonia = Kw / Ka = 1.78 * 10^-5 [Ka = 10^-14]
here NH3 and NH4 + forms a buffer system
by buffer formula ;
pH = pKb + log [NH4+] / [NH3]
initial concentration of NH4 + = 60*10^-6 gm /100ml
per litre =60 *10^-5gms
moles of NH4+ = 3.33*10^-5
concentration in 1 litre = 3.33 * 10^-5 M
pKb = 4.74
keeping in above equation; for pH = 7.2
[NH3] = 9.60 * 10^-3
so moles of NH3 = 9.60 * 10^-3 since took 1 litre.
***Please do process in matlab.****
Thanks in advance (+will upvote good answer).
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