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Question 31 Has human-to-human transmission of the H5N1 avian influenza virus been described? Question 32 In brucellosis, is it possible to see a brucella agglutination test of more than 1/160 even for years after specific and successful therapy of brucellosis?

Question 33 Please define the terms holoendemic, mesoendemic, and hyperendemic in relation to malaria.

Question 34 You only recommend malarone for malarial prophylaxis when there is a significant chlorquine resistance. Isn't malarone now widely used in travellers going to areas with low resistance.

Question 35 Parenteral vaccination with a killed suspension of Vibrio cholerae is recommended by some - isn't an oral vaccine better?

Question 36 Please suggest possible reasons why Entamoeba histolytica infection associated with bloody diarrhoea is not relieved by treatment with ciprofloxacin and metronidazole 400 mg 2 daily over a 3-week period.

Question 37 Is there a basis for treating patients for filariasis according to the eosinophil count (except for cases of tropical pulmonary eosinophils; TPE)? Filariasis is everywhere in my part of the world; a fluorescent antibody test (FAT) might not be very useful - except when there are very high values.

Question 38 Why do patients who ingest eggs from a tapeworm in contaminated food not develop tapeworms?

Question 39 I have a query about one of the details in the book. You mention that perihepatitis is a feature of gonorrhoeal infection, but other books say that perihepatitis (Fitz-Hugh-Curtis syndrome) is a complication of chlamydial infections. Is there a possibility of perihepatitis in gonorrhoea? Thank you.

Question 40 In the 7th edition of Kumar and Clark Clinical Medicine, you indicate that there is no benefit in treating the male partner of a woman diagnosed with bacterial vaginosis (BV). As many physicians use the 2 g 1 metronidazole dose, is this unwarranted? Does it differ in women experiencing frequent recurrences of infection?