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Question 42 Do pulmonary manifestations in Behet's syndrome present with pulmonary infiltrates in the upper zone of the lung?

Question 43 1. Is Behet's disease accompanied by an elevated erythrocyte sedimentation rate (ESR)? If so, how often? 2. Can Behet's disease be diagnosed in a young adult with an ischaemic stroke and a history of almost weekly mouth ulcers that heal quickly, but with no other symptoms of Behet's disease?

Question 44 Mouth ulcers are too common to be a cardinal feature in the diagnosis of Behet's disease. Are there any distinguishing features other than mouth ulcers that would confirm diagnosis?

Question 45 Please explain how to diagnose familial Mediterranean fever. Is a diagnosis of exclusion still used or are there now more up-to-date tools for the diagnosis?

Question 46 Is a leucocytoclastic reaction in a tissue biopsy specific for Henoch-Schnlein purpura or is it also associated with other problems?

Question 47 What are the anatomical, histological and radiological differences between: 1. physis 2. metaphysis 3. epiphyseal disc 4. epiphyseal line?

Question 48 Why does the serum alkaline phosphatase increase in bone disorders and in some other disorders?

Question 49 What is the normal amount of calcium excreted in the urine in a 24-hour period? Question 50 Does hydrochlorothiazide have a prophylactic effect against osteoporosis?

Question 51 How effective is parathyroid hormone in the management of osteoporosis? Please explain the mechanism.

Question 52 1. What is the recommended treatment for severe osteogenesis imperfecta? 2. Where two siblings have already been born with severe osteogenesis imperfecta, what is the risk of subsequent children of the same parents being born with this condition?