Marketing case study. In 2018, 45% of people watch more than an hour of Facebook or YouTube videos a week. A video case study could be a compelling way to attract potential customers who prefer watching a video over reading text. Additionally, a video allows you to convey customer emotion. This case study by Pioneer Business Systems, for instance, allows viewers to see firsthand the effects Pioneer's telephone system had on their clients, ElliotLee Estate Agents. It includes text, as well, to thoughtfully organize and break-up the video into sections.

Question 1

Dear authors, why are gastric ulcers more common along the lesser curve, near the pylorus of the stomach?

Question 2

What is the best time of day to administer omeprazole, and why?

Question 3

Is it safe to use the drugs omeprazole and ranitidine during pregnancy?

Question 4.

Are non-steroidal anti-inflammatory drugs harmful to the stomach when taken parenterally, for example by intravenous or intramuscular routes?

Question 5.

Is it safe to give a patient with a past history of bleeding peptic ulcer aspirin in an antiplatelet dose of 75-325 mg?

Question 6.

Currently favoured regimens for eradication of Helicobacter pylori are triple therapy with a proton pump inhibitor along with two antibiotics for 1 week. For example:

Omeprazole 20 mgmetronidazole 400 mg and clarithromycin 500 mg (all twice daily).

Omeprazole 20 mgclarithromycin 500 mg and amoxicillin 1 g (all twice daily). Resistance to amoxicillin has not yet been demonstrated. Previously, regimens such as omeprazole, metronidazole, amoxicillin and clarithromycin were recommended; are these regimens no longer used? The reason behind this question is the 'sky-high' cost of clarithromycin in Pakistan, which is inversely proportional to patient compliance (that is, low-cost regimens tend to have a higher rate of compliance).

Question 7.

What is the difference between the management of a gastric and of a duodenal ulcer? Question 28 How does omeprazole suppress Helicobacter pylori?

Question 9.

Does omeprazole cause rebound hyperacidity? Does this also apply to H2-blockers?

Question 10.

On (K&C 7e, p. 249), you state that the postsynaptic neurotransmitter that inhibits the relaxation of lower oesophageal sphincter (LOS) is nitric oxide (NO). I have understood NO to promote relaxation of LOS by acting on the non-adrenergic, non-cholinergic (NANC) inhibitory neurones, which inhibits the action of cholinergic excitatory neurones. Could you please explain this paradox?