Marketing is key, whether you're a multibillion dollar company, or just a guy with a cart full of creme brulee. But just doing it isn't enough: you have to market effectively. Curtis Kimball, the man behind the Creme Brulee Cart, put Twitter to work for him amassing thousands of followers and growing his business by allowing people to follow the cart through the online service. Kimball engages with customers and develops a personal relationship with followers online, asking for suggestions on flavors and cart locations. Perhaps the most impressive part of this story is the fact that Kimball has no marketing budget (Twitter is a free service), yet enjoys an incredibly popular status and high ratings on Yelp.

11 What is the advantage of intermittent self-catheterization over an indwelling catheter? How is bladder training done while on an indwelling catheter?

12 Kindly tell me about the role of pulse wave velocity (PWV) in early diagnosis of arteriosclerosis. How is it useful in cardiac, diabetic and renal medicine?

13 You say that no convincing evidence was found that chronic hyperuricaemia causes nephropathy and nor can it be corrected by allopurinol. However, some patients we see have high serum uric acid and creatinine, which both come down with allopurinol. Please comment.

14 Can aspirin cause analgesic nephropathy? If yes, then how could we justify its use in primary prevention of coronary artery disease (CAD), even in high-risk patients? I have read that regular use of analgesics for 3 years could cause analgesic nephropathy

15 What is the probability that a patient on a moderate daily dose of nonsteroidal anti-inflammatory drugs (NSAIDs; ibuprofen 800 mg once daily for tension headache) will develop analgesic nephropathy?

16 Do daily doses of paracetamol with the dosage range of 1 g/day cause analgesic nephropathy. If so, after what length of time?

17 Allopurinol is used for the treatment of uric acid stones; it is also one of the aetiologies of renal calculi. Could you please explain its actual effect.

18 Why should we avoid angiotensin-converting enzyme (ACE) inhibitors as hypertensive therapy in the presence of renal artery stenoses? How can they lead to acute renal failure? What else can we prescribe for this patient to regulate the hypertension?

19 Is the use of angiotensin-converting enzyme (ACE) inhibitors contraindicated in cases of unilateral renal artery stenosis?

20 1. How effective is renal duplex in detecting renal artery stenosis? 2. Is magnetic resonance angiography superior to renal duplex in detecting renal artery stenosis?