Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

mass of catalyst is 0.024mg please help me question 1&2 beripy azdo phenylacelylono: At,30min[Culbr(PPhb) 1.benxy-4-phampl-1H-1,2.3rilambe Figure 1. Copper catalyzed Click coupling to form a triazole.

image text in transcribed
image text in transcribed
mass of catalyst is 0.024mg please help me question 1&2
beripy azdo phenylacelylono: At,30min[Culbr(PPhb) 1.benxy-4-phampl-1H-1,2.3rilambe Figure 1. Copper catalyzed Click coupling to form a triazole. Preparation of 1-benzyl-4-phenyl-1H-1,2,3-triazole. To a 20mL. Wheaton vial, combine the catalyst CuBr(PPh3)3(24mg), benzyl azide (62L) and the phenylacetylene (55L). Add a small magnetic stir bar and cap. After 30 minutes of stirring at room temperature, dissolve the mixture in a small amount of ethyl acetate (2mL ). Filter the solution into a WEIGHED 20mL vial through 2.3cm of silica gel in a plugged (cotton or glass wool) pipet. Rinse the column with a small amount of ethyl acetate (2mL). Remove the ethyl acetate by rotary evaporation/vacuum. Heat your product in the vial to around 60C to remove any 1. What is the role of the catalyst in a reaction? How many molar equivalents of the catalyst were added versus the reagents (show your calculations using equation editor)? Why is only a small fraction of the catalyst required (in regard to the reagents) for preparation of the triazole? 2. What is the purpose of the short column in the preparation of the triazole? 3. What is the purpose of the rotary evaporator/vacuum? 4. What is the melting point range of your final product? 5. How does this value compare to the values given in your protocol and what information does this provide? If you only obtained an oil, assume you obtained a melting point range of 119124C and answer the question using that data. 6. Calculate the atom economy, theoretical and percent yield for the final traizole product you collected. (Note: Do not include the catalyst in your calculations for this sten.) Please provide.all of vour data (starting masses

Step by Step Solution

There are 3 Steps involved in it

Step: 1

blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Quantitative Chemical Analysis

Authors: Daniel C. Harris

9th Edition

146413538X, 978-1464135385

More Books

Students also viewed these Chemistry questions