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Medical researchers are interested in which of two drugs are effective in treating chronic headaches. One set of five patients suffering from headaches received drug
Medical researchers are interested in which of two drugs are effective in treating chronic headaches. One set of five patients suffering from headaches received drug A for one month; another set of four patients received Drug B. The number of pain-free days experienced by each patient is recorded in the table below: Pain-Free Days Drug 1 2 3 4 5 Mean Variance A 22 30 18 15 19 20.8 32.7 B 17 14 11 7 12.25 18.25 A bootstrap simulation was performed in which 1000 data sets of size 9 were regenerated from the original data, and split into two groups of size 5 and 4 respectively. The resultant differences in means (B - A) from the two groups were sorted from smallest to largest. A summary of the differences observed at various positions in the sorted list are given as follows: Position: 1 5 10 50 100 Value: -14.0 -11.4 -10.2 -7.1 -5.6 Position: 900 950 990 995 1000 Value: 5.3 7.1 10.2 11.0 15.7(3) Use the bootstrapped data to estimate the p-value for the test of differences between the means. (b) Use the bootstrapped data to construct a 99% confidence interval for the difference between the means
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