Mitsui Bank hired Ross Duncan as a branch manager in one of its Southern California locations. At that time, Duncan received an employee handbook informing him that Mitsui would review his performance and salary level annually. In 2018, Mitsui decided to a new lending program to help financially troubled businesses stay afloat. It promoted Duncan to be the credit development officer (CDO) and gave him a written compensation plan. Duncan's compensation was to be based on the new program's success and involved a bonus and commissions based on new loans and sales volume. The written plan also stated, "This compensation plan will be reviewed and potentially amended after one year and will be subject to such review and amendment annually thereafter."

21 What else could we use instead of propranolol in thyrotoxicosis with bronchial asthma?

22 At what dose, and for how long, would steroid therapy give rise to secondary adrenal insufficiency? For adrenal insufficiency due to longterm steroid use, when should we start to give a cortisone supplement? How should we monitor these patients?

23 What dose of Synacthen is equivalent to adrenocorticotrophic hormone (ACTH)?

24 I want to know the mechanism that causes anaemia in Addison's disease. I am unable to find the real cause.

25 What causes hypercalcaemia in Addison's disease?

26 In the diagnosis of Cushing's disease using the high-dose dexamethasone suppression test, how can the exogenous steroid suppress adrenocorticotrophic hormone (ACTH) when the grossly elevated serum cortisol levels fail to do so?

27 Does alternate-day therapy with steroids decrease their efficacy compared with daily therapy?

28 Regarding the renin-angiotensin-aldosterone axis, it states that dietary sodium excess suppresses renin secretion. Then why are we asking hypertensives to restrict sodium intake? Also if we are using angiotensinconverting enzyme (ACE) inhibitors, the plasma renin activity increases due to loss of feedback inhibition. Wouldn't that be counterproductive?

29 How does a phaeochromocytoma give rise to Raynaud's phenomenon?

30 How well do symptoms of hypercalcaemia correlate with serum calcium levels. Can I ignore an asymptomatic patient with a serum calcium of 3.7 mmol/L but have to give treatment to a symptomatic patient who has a serum calcium of 3.3 mmol/L?