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Montgomery 6.4.9 An article inNature Genetics[Treatment-specific Changes in Gene Expression Discriminate In Vivo Drug Response in Human Leukemia Cells (2003, Vol. 34(1), pp. 85-90)] studied

Montgomery6.4.9An article inNature Genetics["Treatment-specific Changes in Gene Expression Discriminate In Vivo Drug Response in Human Leukemia Cells" (2003, Vol. 34(1), pp. 85-90)] studied gene expression as a function of treatments for leukemia. One group received a high dose of the drug, while the control group received no treatment. Expression data (measures of gene activity) from one gene are shown in the excel file "Gene data".

Using this data create report which graphically and statistically describes the data and then state if you think there is a difference between the 2 groups. What issues do you see in evaluating this data? This report should be no longer than of written text, tables, graphs or figures (in total), excluding and any included appendixes.

High Dose 20.3 170 66.4 18.1 156.6 124.7 30.6 20.5 19.2 60.1 16.3 91.6 159.6 58.5 76 29.6 54.9 100 47.9 73.3 33.4 31.6

Control 407 673.8 1826.1 1605.6 2031.3 459.5 724.6 33 746.9 127.3 461.8 140.2 349.5 137.7 219.1 230.2 130.4 181.5 606.4 21.6 240.6 179.6 1123.5 113 978 1076.3 156.2 43.7 118.2 885.8 232.8 27.7 383.9 266.1 559.5 213 1184.5 486.9 868.6 2781 496.1 228.1 3094 681.6 360.9 345.7 481.4 930.1 4124 91.9 435.9 3392.7 248.5 2851.7 581.3 257.7 771.3 204.3 2908.4 1775.4

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