MPH 604 Week 2 Calculations Measures of Disease Burden Show all your work for the best possible evaluation of your responses. 1. The population of Metroville was 7,832,687 on January 1, 2015 and 7,436,355 on December 31, 2015. During 2015, a total of 9,209 residents were HIV positive. Of these cases, 452 cases were newly diagnosed cases of HIV. Calculate the prevalence and incidence per 100,000 population for the year 2015. 2. A cancer clinic wished to study incidence rate of skin cancer cases in sunny Miami, Florida. They studied 1000 patients for 10 years, with visits every 2 years. They found the following: at the first visit (2 years into the study), there were 18 cases of cancer. At visit two, there were 12 cases of cancer and 9 women were lost to follow up. At visit three, there were 8 cancer cases; at visit four, there were 5 cancer cases and 23 women were lost to follow-up. At the final visit, there were 6 cancer cases. Calculate the person-time and the incidence density (incidence rate). Please show all work. 3. In 2000, there were 3,600 deaths due to lung diseases in miners aged 20 to 64 years. The expected number of deaths in this occupational group, based on age-specific deaths rates from lung diseases in all males aged 20 to 64 years, was 1,200 during 2000. What is the standardized mortality ratio (SMR) for lung disease in miners? Interpret this ratio. 4. Please review the figure below and comment on difference between the crude death rate and the age-adjusted death rate over time. What overall conclusion do you draw? Xu J et al. (2016). Deaths: Final Data for 2013. National Vital Statistics Reports; 64(2):1-119. 5. What is the age-adjusted mortality rate for residents of Florida using the age distribution for residents of Minnesota? Show your calculations in tabular form. Is this the direct or indirect method for age adjustment? 1 MPH 604 Week 2 Calculations Florida Age Group < 1 year 1-4 years 5-9 years 10-14 years 15-19 years 20-24 years 25-34 years 35-44 years 45-54 years 55-64 years 65-74 years 75-84 years 85+ years Total Deaths 1,669 304 125 148 775 1,455 2,909 5,166 12,476 19,147 27,483 46,128 52,910 170,695 Population 222,151 863,428 1,065,778 1,134,890 1,241,381 1,207,898 2,250,501 2,513,608 2,674,832 2,217,834 1,632,942 1,096,681 405,381 18,527,305 Minnesota Crude rate per 100,000 751.3 35.2 11.7 13 62.4 120.5 129.3 205.5 466.4 863.3 1,683.00 4,206.10 13,051.90 921.40 Deaths 434 80 41 46 132 246 503 910 2,390 3,870 5,530 9,982 14,335 38,499 Population 71,839 283,606 347,065 354,831 377,663 361,413 693,862 711,830 803,929 582,155 333,565 222,112 103,148 5,247,018 Crude rate per 100,000 604.1 28.2 11.8 13 35 68.1 72.5 127.8 297.3 664.8 1,657.80 4,494.10 13,897.50 733.7 Centers for Disease Control and Prevention, National Center for Health Statistics. Compressed Mortality File 1999-2014 on CDC WONDER Online Database, released December 2015. Data are from the Compressed Mortality File 1999-2014 Series 20 No. 2T, 2015, as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program. Accessed at http://wonder.cdc.gov/cmf-icd10.html on Sep 19, 2016 4:14:46 PM 2