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need help The goal of this assignment is to give you more practice identifying if a reaction will go through an SN1, SN2, E1, or
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The goal of this assignment is to give you more practice identifying if a reaction will go through an SN1, SN2, E1, or E2 mechanism. The problems are designed to first help you determine the correct mechanism so that you can provide the correct products. If do not have the SN1, SN2, E1, E2 summary, a file can be found on Canvas on the Chapter 7-9: handouts page. I encourage you to have this available as you answer the questions. For each reaction: a. Circle the appropriate properties associated with the reagents for the reaction in part c. Remember that that the electron donor in the reaction much be considered as both a nucleophile and a base, b. Based on your selections in part a, identify the reaction mechanism as either SN1/E1, SN2 or E2. c. Provide the major product(s) for the reaction. Clearly indicate the stereochemistry in your structures where appropriate. Where more than one stereoisomer is formed you only need to draw one of the stereoisomeric products. Other stereoisomers should be indicated by writing, "+enantiomer" or "+diastereomer", as appropriate. Check the boxes on the right to indicate whether the reaction product. solution would be optically active ([]0=0) or not optically active ([]0=0). Under the checkboxes give your rationale for the selection using one of the following: achiral, racemic, meso, single enantiomer, mixture of diastereomers. Solvent: polarprotic polar aprotic 1b) Overall mechanism: SN1/E1 SN2 1c) []D=0[]D=0 2a) Electrophilic carbon/substrate: Methyl Primary Secondary Tertiary Nucleophile: good nucleophile poor nucleophile Base: strong base strong, bulky base goodbase goodbulky base poorbase Solvent: polar protic polar aprotic 2b) Overall mechanism: SN1/E1 SN2 E2 2c) (CH3)2CHOH []D=0[]D=0 3a) Electrophilic carbon/substrate: Methyl Primary. Secondary Tertiary Nucleophile: good nucleophile poor nucleophille Base: strong base strong, bulky base good base good bulky base poor base Solvent: polarprotic polar aprotic 3b) Overall mechanism: SN1/E1 5NN2 3c) 4a) Electrophilic carbon/substrate: Methyl Primary Secondary Tertiary Nucleophile: good nucleophile poor nucleophile Ease: strong base strong, bulkybase goodbase goodbulkybase poor base Solvent: polar protic polar aprotic Ab) Overall mechanism: SN1/E1 SN2 E2 4c) (CH2)2COH(CH2)2COK Step by Step Solution
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