Needed urgently. Imagine you are currently in position 2 of a paid search term, the click-through rate (clicks per impression) is 1% and the cost per click is $1.50.You can get into position 1, where the click-through rate is 1.8%, by paying $2.50 per click. In position 3 you would pay $0.75 per click, and have a click-though rate of 0.6%.Conversion rate (orders per click) once someone clicks is 10% in all 3 positions.Our total profit per order (before search advertising costs) is $30.There are 50,000 searches per day that our ad will display on. It will display in the same position each time; you cannot pick a mix of positions.Our goal is to maximize the total profit after search advertising costs.

QuestionsA)What is the cost per order in each position? B)Which of the three positions do we want to be in?C)What is the cost per order of just the orders you gain by moving up from position 3 to position 2?D)What is the minimum acceptable click-through rate for for us to prefer position 1 for our ads? Put another way, what is the rate where we are indifferent between position one and the next best position?E)Imagine, in addition to the information above, we now also have a daily budget of just $600. Which position do we want to be in now?

Question 1 Do non-obese patients with impaired fasting glucose, i.e. a glucose level of 6.1-6.9 mmol/L, need drug treatment with biguanides if lifestyle modifications fail to normalize? Question 15 Do non-obese patients with impaired glucose tolerance (but not fulfilling the criteria for diabetes mellitus) need drug treatment with biguanides if lifestyle modifications fail to normalize their post-prandial blood glucose measurements? Question 16 It is the Muslim month of fasting currently. I would be grateful if you could advise on how to adjust the insulin regimen of a type 1 diabetic patient, for example a 21-year-old girl who is on subcutaneous Actrapid (short-acting soluble insulin) 22 units t.d.s. Question 17 I would like to know more about the use of the glitazone group in type 2 diabetes: its action, side-effects, precautions taken on using them. Question 18 In a patient receiving oral antidiabetics, should the drug be administered just after taking the blood sample for fasting blood glucose level (and before a meal), or just prior to the sample being taken? Question 19 What oral antidiabetics are safe in pregnancy? Question 20 Is it necessary to put all type 2 diabetics on aspirin? Question 21 In the chapter on diabetes you wrote that you should avoid tablets before age of 40 years in non-insulin-dependent diabetes mellitus (NIDDM). Why is this, because in our country most doctors are prescribing this? Question 22 1. Should a patient poorly controlled on glibenclamide 15 mg a day and metformin 1500 mg a day be moved onto insulin? 2. What are the indications for insulin in type 2 diabetics? Question 23 What happens to the insulin-secreting capacity of a type 2 diabetic placed on insulin therapy earlier than recommended? Can the external supply of insulin improve the functional capacity of the insulin-secreting cells, to some extent by providing some rest to these cells?