of a gel diffusion barrier.

A3cm\\\\times 3cm

patch has a diffusion barrier with a thickness of

2.0mm

. The diffusion barrier is in direct contact with the skin. The drug release vs. time profile is shown below. The drug is only slightly soluble in the gel diffusion barrier, with a maximum solubility of

0.5\\\\mu mo(l)/(c)m^(3)

at the top of the barrier. Other experiments show the drug is immediately absorbed into the bloodstream after exiting the patch (i.e., it is instantly cleared).\ a. State the boundary conditions for this system.\ b. Explain why this system can be modeled as steady-state.\ c. Solve the differential mass balance to find the concentration profile.

of a gel diffusion barrier. A 3cm3cm patch has a diffusion barrier with a thickness of 2.0mm. The diffusion barrier is in direct contact with the skin. The drug release vs. time profile is shown below. The drug is only slightly soluble in the gel diffusion barrier, with a maximum solubility of 0.5mol/cm3 at the top of the barrier. Other experiments show the drug is immediately absorbed into the bloodstream after exiting the patch (i.e., it is instantly cleared). (sink for drug) a. State the boundary conditions for this system. b. Explain why this system can be modeled as steady-state. c. Solve the differential mass balance to find the concentration profile