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Oxygenating Blood When arterial blood enters a tissue capillary, it exchanges oxygen and carbon dioxide with its environment, as shown in this diagram. The kinetics
Oxygenating Blood
When arterial blood enters a tissue capillary, it exchanges oxygen and carbon
dioxide with its environment, as shown in this diagram.
The kinetics of this deoxygenation of hemoglobin in blood was studied with the
aid of a tubular reactor by Nakamura and Staub J Physiol.,
Although this is a reversible reaction, measurements were made in the initial
phases of the decomposition so that the reverse reaction could be neglected.
Consider a system similar to the one used by Nakamura and Staub: the
solution enters a tubular reactor in diameter that has oxygen
electrodes placed at intervals down the tube. The solution flow rate into
the reactor is
Using the method of differential analysis of rate data, determine the reaction
order and the forward specific reaction rate constant for the deoxygenation
of hemoglobin.
If you were to take more data points, what would be reasonable points?, why?
Hint: Estimate the inlet concentration of by using typical values of
hemoglobin concentration in adult human blood, and by assuming that
hemoglobin is saturated with oxygen, consider the position of the electrode as
the time
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