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Paclitaxel, the generic name for the chemotherapy drug Taxol,was first isolated from the bark of a Western yew tree. Taxolsmechanism of action is inhibition of
Paclitaxel, the generic name for the chemotherapy drug Taxol,was first isolated from the bark of a Western yew tree. Taxol’smechanism of action is inhibition of microtubule formation andblockage of mitosis. Why do you think these trees produce thischemical compound? Why might tree growth not be inhibited by thepresence of paclitaxel in the bark?
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