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Paroxetine (Paxil) is an antidepressant that is a member of a family of drugs known as Selective Serotonin Reuptake Inhibitors (5SRIs). This tamily of drugs

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Paroxetine (Paxil) is an antidepressant that is a member of a family of drugs known as Selective Serotonin Reuptake Inhibitors (5SRIs). This tamily of drugs also includes fluoxetine (Prozac) and sertraline (Zoloft). SSRIs work by inhibiting the reuptake of the neurotransmitter serotonin in the synapses of the central nervous system following release of serotonin during excitation of individual nerve cells. Between firings, the serotonin is taken back up by a nerve cell in preparation for firing again. Inhibition of reuptake has the effect of increasing the time serotonin molecules remain in the synapses following excitation, leading to a therapeutic effect. In one synthesis of paroxetine, the following reagents are used. Draw the structure of synthetic intermediate A. PyridineSOCl2A - Use the wedge/hash bond tools to indicate stereochemistry where it exists. - Should you want to restart the exercise, the drop-down menu labeled == starting points == can be used to redraw the starting molecule on the sketcher

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