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Please answer ALL PARTS step by step. NO copy & paste answers PLEASE 1. The peptide Special K forms an -helix that is broken at
Please answer ALL PARTS step by step. NO copy & paste answers PLEASE
1. The peptide Special K forms an -helix that is broken at high temperatures. The fraction of peotide in the -helical form. . was measured over a range of temoeratures: HT(K a. Calculate the equilibrium constant, Keq, and standard free energy for helix formation, G, at 324.4K. b. What is the sign of H (i.e., positive or negative) for the formation of an -helix at this temperature? Provide a brief explanation for its sign. c. Special K contains one histidine residue. Calculate the fraction of Special K molecules in which the histidine is positively charged at 25C and pH7.0. d. As the temperature of the peptide is increased, the Ka of the histidine residue will change. Note from Table 4.2 that the H for the dissociation of a histidine side chain (i.e., transition of charged to uncharged) is +29.9kJ/mol. Based on this, will the fraction of charged histidine residues increase or decrease as the temperature is raised from 25C to 54.4C at pH 7? You don't need to calculate a value, but explain your reasoningStep by Step Solution
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