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please help , and explain In Class learning activity # 1 PHM 323 A single intravenous injection of 1.5 mg/kg of drug A is administered
please help , and explain In Class learning activity # 1 PHM 323 A single intravenous injection of 1.5 mg/kg of drug A is administered to a 33 year old male subject (Weight = 80kg). The following plasma concentrations are collected: In(C) Time (hours) 1 2 4 8 12 24 Conc. (ug/mL) 1.26 1.06 0.75 0.38 0.19 0.02 From the data provided Calculate the following: Value Units Parameter CO K V 112 AUCO CL IgM In Class learning activity # 1 IPHM 323 Fraction of dose @12h Number of t12 to eliminate 90% of dose Predict the following: Value Units So for a 6 mg/kg dose The plasma concentration (@t- 12 h for the 6 mg/kg dose Fraction of dose 12h In Class learning activity # 1 PHM 323 A single intravenous injection of 1.5 mg/kg of drug A is administered to a 33 year old male subject (Weight = 80kg). The following plasma concentrations are collected: In(C) Time (hours) 1 2 4 8 12 24 Conc. (ug/mL) 1.26 1.06 0.75 0.38 0.19 0.02 From the data provided Calculate the following: Value Units Parameter CO K V 112 AUCO CL IgM In Class learning activity # 1 IPHM 323 Fraction of dose @12h Number of t12 to eliminate 90% of dose Predict the following: Value Units So for a 6 mg/kg dose The plasma concentration (@t- 12 h for the 6 mg/kg dose Fraction of dose 12h
please help , and explain
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