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please show work and explain, i'm trying to figure out how to do it as well. What is the most acidic proton in this molecule?

please show work and explain, i'm trying to figure out how to do it as well.
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What is the most acidic proton in this molecule? (i.e. which one will dissociate first?) - A1 - B - 2 - C - 3 - D - 4 - E - The carbons! Clicker Question 3: Based on the arrow pushing, what would be the product

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