Please use pictures to see the tables as reference

Part 1: Transcription and Translation

1. Transcribe the following DNA sequence from HbA. Record your answer inData Table 1. to submit for grading.Hint:You are given the coding strand (the coding strand is always given in the 5' to 3' direction). The coding strand has the same sequence as the mRNA produced during transcription, exceptTis replaced withU. So your answer will be the same 5' to 3' sequence as the DNA coding strand, except the T's will be replaced with U's. 5' - AGT AAC GGC AGA CTT CTC CTC AGG AGT CAG GTG CAC CAT - 3'
2. Translate the following mRNA sequence. Record your answer inData Table 1. 5' - AUG GUG CAC CUG ACU CCU GAG GAG AAG UCU GCC GUU ACU - 3'
3. Transcribe the following DNA sequence from HbA. Record your in Data Table 1.Hint:You are given the coding strand (the coding strand is always given in the 5' to 3' direction). The coding strand has the same sequence as the mRNA produced during transcription, exceptTis replaced withU. So your answer will be the same 5' to 3' sequence as the DNA coding strand, except the T's will be replaced with U's. 5' - AGT AAC GGC AGA CTT CTC CAC AGG AGT CAG GTG CAC CAT - 3'
4. Translate the following mRNA sequence. Record your answer inData Table 1. 5' - AUG GUG CAC CUG ACU CCU GUG GAG AAG UCU GCC GUU ACU - 3'

Part 2: Genetic Mutations

RNA sequences are conventionally written in the 5' to 3' direction because this is the direction RNA is synthesized and read during translation.

1. Given the following 5' to 3' RNA sequence, translate each codon into its respective amino acid working left to right in the 5' to 3' direction. Use the 3 letter amino acid designation in your answer with a space between each amino acid to report your trasnlated amino acid sequence. For example, type your answer like the following example: Lys His Ser Asp etc.. Use STOP instead of the 3 letter amino acid designation if you encounter a stop codon. Record your amino acid sequence in Data Table 2. AUG GAG GUC UUU AAG AGA CAU UUA GAU GUA GCC CUU AGU GAU GUU UAG
2. Create one or more point mutations in this sequence. Record your point mutation inData Table 2. AUG GAG GUC UUU AAG AGA CAU UUA GAU GUA GCC CUU AGU GAU GUU UAG
3. Translate your mutated sequence. Record your translation inData Table 2.
4. Now, create a frameshift mutation by adding one or more bases. Record your frameshift mutation inData Table 2. AUG GAG GUC UUU AAG AGA CAU UUA GAU GUA GCC CUU AGU GAU GUU UAG
5. Translate your mutated sequence. Record your translation inData Table 2.
6. Create a frameshift mutation by deleting one or more bases. Record your frameshift mutation inData Table 2. AUG GAG GUC UUU AAG AGA CAU UUA GAU GUA GCC CUU AGU GAU GUU UAG
7. Translate your mutated sequence. Record your translation inData Table 2.

Part 1: Transcription and Translation 1 Transcribe the following DNA sequence from HbA. Record your answer in Data Table 1. to submit for grading. Hint: You are given the coding strand (the coding strand is always given in the 5' to 3' direction). The coding strand has the same sequence as the mRNA produced during transcription, except Tis replaced with U. So your answer will be the same 5' to 3' sequence as the DNA coding strand, except the T's will be replaced with U's. 5' - AGT AAC GGC AGA CTT CTC CTC AGG AGT CAG GTG CAC CAT - 3' 2 Translate the following mRNA sequence. Record your answer in Data Table 1. 5' - AUG GUG CAC CUG ACU CCU GAG GAG AAG UCU GCC GUU ACU - 3' 3 Transcribe the following DNA sequence from HbA. Record your in Data Table 1. Hint: You are given the coding strand (the coding strand is always given in the 5' to 3' direction). The coding strand has the same sequence as the mRNA produced during transcription, except T is replaced with U. So your answer will be the same 5' to 3' sequence as the DNA coding strand, except the T's will be . . . Experiment 1 Table 1 Table 2 Table 1: Transcription and Translation MRNA Type answer here Sequence 1 (5' to 3') Protein Type answer here Sequence 1 MRNA Type answer here Sequence 2 (5' to 3') Type answer here Sequence 2anoption, Translation, anTa Macatro The Central Dogma states that DNA is transcribed to mRNA, which is then translated to protein. In Part 1, you will transcribe and translate short segments of the proteins hemoglobin A (HbA) and hemoglobin S (HbS). In Part 2 of this exercise, you will create mutations in a RNA sequence and observe how these mutations impact the translated amino acid structure. Procedure Part 1. Transcription and Translation . . . Experiment 1 Table 1 Table 2 with Point Mutation RNA Coding ype answer here Strand with Frame Shift Mutation (Addition) Protein Type answer here Sequence with Frame Shift Mutation (tion) RNA CodingThe Central Dogma states that DNA is transcribed to mRNA, which is then translated to protein. In Part 1, you will transcribe and translate short segments of the proteins hemoglobin A (HbA) and hemoglobin S (HbS). In Part 2 of this exercise, you will create mutations in a RNA sequence and observe how these mutations impact the translated amino acid structure. Procedure Part 1. Transcription and Translation . . . Experiment 1 Table 1 Table 2 Table 2: Genetic Mutations RNA Coding |AUG|GAG|GUCUUU|AAG|AGA|CAU|UUA|GAU|GUA|GCC|CUU|AGU|GAU|GUU|UAG Strand Protein Type answer here Sequence RNA Coding Type answer here Strand with Point Mutation Protein Type answer here s ence with PointThe Central Dogma states that DNA is transcribed to mRNA, which is then translated to protein. In Part 1, you will transcribe and translate short segments of the proteins hemoglobin A (HbA) and hemoglobin S (HbS). In Part 2 of this exercise, you will create mutations in a RNA sequence and observe how these mutations impact the translated amino acid structure. Procedure Part 1. Transcription and Translation . . . Experiment 1 Table 1 Table 2 IVIutation (Addition) RNA Coding Type answer here Strand with Frame Shift Mutation (Deletion) Protein Type answer here Sequence with Frame Shift Mutation ([tion)