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Problem 3 (7 pts): Urea is degraded by uricase enzyme immobilized in porous Caalginate beads. The diffusion coefficient of urea within the spherical support is

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Problem 3 (7 pts): Urea is degraded by uricase enzyme immobilized in porous Caalginate beads. The diffusion coefficient of urea within the spherical support is De=310 4cm2/min; the particle diameter is Dp=0.2cm; the observed rate of urea hydrolysis is 180 mol/cm3min; Thiele Modulus () is estimated at 4.5; the urea concentration in bulk liquid is 20mol/cm3. Assume negligible liquid film resistance. (Note: = 3[tanh11]) a) (2 pts) Is there diffusional limitation? Justify the answer based on the value of . b) (2pts) What would be the observed rate if there were no diffusion limitations? c) (3pts) Will increasing particle size alleviate diffusion limitations of the enzyme system? Justify your

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