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Provide a detailed arrow pushing mechanism for the follow transformation. 4. (34 pts) Provide a detailed arrow pushing mechanism for the following transformations. (10 points)

Provide a detailed arrow pushing mechanism for the follow transformation.image text in transcribed

4. (34 pts) Provide a detailed arrow pushing mechanism for the following transformations. (10 points) The growth of new blood vessels angiogenesis is a crucial mbryonic development. Abnormal angiogenesis is associated with tumor growth, suggesting that inhibition of angiogenesis may be an approach for the treatment of cancer. The diepoxide, ovalicin, is an angiogenesis inhibitor that was synthesized from compound C, which was in turn prepared from compound A by a two-step sequence. First, draw the structure for compound B. Second, draw a mechanism for the conversion of B to C. A -toluenesulfonyl chloride B

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