Q3. A transdermal system is designed to deliver a drug consistently over a 34 day period when placed on the skin. For a 36cm2 patch, the release rate of the drug is 1 mg per day. Clinical trials have provided the following pharmacokinetic data. In one study, following application of the patch, the peak concentration of the drug was found to be 144pgmL1, and the half-life of the drug was found to be 1h. Over an 84 h dosing interval, the plasma clearance for drug from the patch was found to be 61 Lh1. (i) What is the steady state plasma concentration for drug in pg per mL? (ii) If the drug profile follows a curve as given below, calculate the total drug concentration available during the first 24h