Question 1: By examining the single channel recordings above, identify which (time-course) diagram (i, ii or iii) best describes the final equilibrium distribution of these channels for a step to +40mV (from -100mV)?

Question 2: Which rate constant is larger at -100mV (kO-C or kC-O)? Which rate constant is larger at +40mV (kO-C or kC-O)?

Question 3: Notice that the concentration units above (in part a) are in units of %concentration. What this means is that the graph is showing relative numbers. How would you estimate the probability of the channels being in the O versus C states from these graphs?

Question 4: Explain why for isomerizations reactions it is always possible (in principle) to estimate the probability of being in the O state and the probability of being in the C state.

Please answer each question separately and according to the given graph, thanks

Cd[C]/dt=ko=kc0[C]+kOc[O]