Question $21$

Which of the following essential documents must be available before the trial starts? $($choose the best answer$)$

A$.$ the protocol, the investigator$$s brochure, the contract with third parties $($CRO$),$ the source documents

B$.$ the protocol, the decoding procedures in blind studies, the documentation of CRF corrections, monitoring reports

C$.$ the financial agreement between the sponsor and the investigator, trial insurance, samples of CRF$,$ monitoring plan

D$.$ the subject identification code list, regulatory approval, normal lab ranges, instruction for IMP storage