Question 49: In a typical 24-hour period, how much calcium is excreted in the urine? Rheumatology and bone disease 10 91 Question 51 How effective is parathyroid hormone in the management of osteoporosis? Does hydrochlorothiazide have a prophylactic effect against osteoporosis?Please describe the operation. 52. QuestionFor severe osteogenesis imperfecta, what is the recommended course of treatment?2.How likely is it that subsequent children of the same parents will be born with severe osteogenesis imperfecta if two siblings already have the condition? When all other bones are affected, why does achondroplasia not affect the mandible? Question 54: Should an elderly person with rheumatoid arthritis who has been taking myocrisin (injectable gold) for a number of years experience pancytopenia?Which treatment should take its place, if so? Question 55: What laboratory tests should be ordered to rule out systemic lupus erythematosus (SLE) in a patient with dermatomyositis? Question 56: What kind of treatment for tarsal tunnel syndrome is recommended? Should a lupus anticoagulant be investigated in a patient with documented antiphospholipid syndrome?Will the use of anticoagulants be necessary if it is discovered? In patients receiving long-term chloroquine or any other antimalarial therapy for the treatment of systemic lupus erythematosus (SLE), what findings should be looked for during a routine fundus examination? Question 59: Is there a specific diagnostic test for detecting ankylosing spondylitis-related spine lesions in both early and late disease? What is the sensitivity of plain X-ray?